<p><strong>For Research Use Only</strong></p>
<p>Kisspeptin is a naturally occurring neuropeptide encoded by the KISS1 gene, originally identified as a metastasis suppressor before its critical role in reproductive endocrinology was established. It is the endogenous ligand for the kisspeptin receptor (KISS1R, also known as GPR54), and has since been recognized as one of the most potent known activators of the hypothalamic-pituitary-gonadal (HPG) axis. Research has extensively investigated Kisspeptin for its role as a master regulator of gonadotropin-releasing hormone (GnRH) secretion, with studies demonstrating its ability to stimulate GnRH pulse generation from hypothalamic neurons, thereby driving downstream luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release from the pituitary gland. Studies have explored its involvement in the regulation of puberty onset, seasonal reproductive cycles, and the integration of metabolic and environmental signals into reproductive axis activity. Research has also investigated Kisspeptin's role in sex steroid feedback mechanisms, with studies indicating its neurons in the arcuate nucleus serve as critical mediators of both negative and positive estrogen feedback on GnRH secretion. Additional research has explored its potential involvement in sexual behavior, placental function, and glucose homeostasis, highlighting Kisspeptin as a multifunctional neuropeptide with a broad and rapidly expanding research profile in reproductive and metabolic biology.</p>
<h4>Specifications</h4>
<table>
<tbody>
<tr><td><strong>Format</strong></td><td>Lyophilized powder</td></tr>
<tr><td><strong>Molecular Formula</strong></td><td>C₆₃H₈₃N₁₅O₁₄S</td></tr>
<tr><td><strong>Purity</strong></td><td>≥ 99% (HPLC verified)</td></tr>
<tr><td><strong>Appearance</strong></td><td>White/off-white powder</td></tr>
<tr><td><strong>Storage</strong></td><td>Store at −20 °C (lyophilized); refrigerate after reconstitution</td></tr>
<tr><td><strong>Packaging</strong></td><td>Sterile, sealed 10 mg vial</td></tr>
</tbody>
</table>
<h4>Intended Use</h4>
<p>This compound is provided exclusively for laboratory research purposes, including studies on HPG axis regulation, GnRH secretion, reproductive endocrinology, kisspeptin receptor signaling, and neuroendocrine biology. It is not approved for human consumption, medical, veterinary, or diagnostic use.</p>
<h4>Important Notice</h4>
<ul>
<li>Not for human or animal use</li>
<li>Not for therapeutic or diagnostic applications</li>
<li>Handle only by qualified laboratory professionals</li>
</ul>
